Alpha1-antitrypsin deficiency--a literature review and a case report of a patient with chronic obstructive airways disease and cirrhosis.

Abstract

A patient who manifested both pulmonary and hepatic disease associated with alpha1-antitrypsin deficiency is described. The biological function of alpha1-antitrypsin is discussed, as well as the inheritance of deficiency states and the spectrum of disorders which may ensue. Severe deficiency of alpha1-antitrypsin has been linked with pulmonary emphysema in adult life, progressive liver disease in childhood, adult cirrhosis but rarely with both pulmonary and liver disease.

Cite this paper

@article{Coughlin1977Alpha1antitrypsinDL, title={Alpha1-antitrypsin deficiency--a literature review and a case report of a patient with chronic obstructive airways disease and cirrhosis.}, author={Gabrielle Coughlin and A G van Deth and G T Ey and Aaron K. Grant}, journal={Australian and New Zealand journal of medicine}, year={1977}, volume={7 4}, pages={400-3} }