Alpha s1-casein-specific CD8+ T cell clone that inhibits its own interferon-gamma production by producing interleukin-10.

Abstract

A CD8+ T cell clone specific to alpha s1-casein, one of the major allergens in milk, is shown to inhibit its own production of interferon (IFN)-gamma by producing interleukin (IL)-10. Anti-IL-10 antibodies enhanced the production of IFN-gamma induced by the antigen plus antigen-presenting cells from 12 h onward after initiating the culture. This enhancing… (More)

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