Alpha-particle Monte Carlo simulation for microdosimetric calculations using a commercial spreadsheet.

@article{Roeske2007AlphaparticleMC,
  title={Alpha-particle Monte Carlo simulation for microdosimetric calculations using a commercial spreadsheet.},
  author={John C. Roeske and Mark Hoggarth},
  journal={Physics in medicine and biology},
  year={2007},
  volume={52 7},
  pages={1909-22}
}
Alpha-particle emitters are currently being evaluated in the treatment of cancer. Because of the short range and high linear energy transfer (LET) of most therapeutic alpha-particle emitters, there are significant stochastic variations in the energy deposited within the cellular nucleus. Hence microdosimetric spectra are often necessary to interpret biological endpoints. However, alpha-particle microdosimetric codes are not readily available. In this paper, we describe how a commercial… CONTINUE READING

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