Alpha-methyldopa disposition in mothers with hypertension and in their breast-fed infants.

Abstract

To assess the problem of alpha-methyldopa dosing in lactating mothers with hypertension, we studied three breast-feeding women to determine simultaneous plasma and breast milk concentrations of alpha-methyldopa after a 500 mg oral dose while receiving continuous therapy. Peak excretion of free alpha-methyldopa in breast milk ranged from 0.02 to 1.14… (More)

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Cite this paper

@article{White1985AlphamethyldopaDI, title={Alpha-methyldopa disposition in mothers with hypertension and in their breast-fed infants.}, author={Wesley White and J W Andreoli and Ronald D. Cohn}, journal={Clinical pharmacology and therapeutics}, year={1985}, volume={37 4}, pages={387-90} }