Alpha-lipoic acid improves subclinical left ventricular dysfunction in asymptomatic patients with type 1 diabetes.

@article{Hegazy2013AlphalipoicAI,
  title={Alpha-lipoic acid improves subclinical left ventricular dysfunction in asymptomatic patients with type 1 diabetes.},
  author={S. Hegazy and Osama A. Tolba and T. Mostafa and M. Eid and Dalia R El-Afify},
  journal={The review of diabetic studies : RDS},
  year={2013},
  volume={10 1},
  pages={
          58-67
        }
}
BACKGROUND Oxidative stress plays an important role in the development of diabetic cardiomyopathy. Alpha-lipoic acid (ALA) is a powerful antioxidant that may have a protective role in diabetic cardiac dysfunction. AIM We investigated the possible beneficial effect of alpha-lipoic acid on diabetic left ventricular (LV) dysfunction in children and adolescents with asymptomatic type 1 diabetes (T1D). SUBJECTS AND METHODS Thirty T1D patients (aged 10-14) were randomized to receive insulin… Expand
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References

SHOWING 1-10 OF 51 REFERENCES
alpha-Lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria.
Glycaemic control, markers of endothelial cell activation and oxidative stress in children with type 1 diabetes mellitus.
Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications.
Altered redox status in patients with diabetes mellitus type I.
Erythrocyte susceptibility to oxidative stress and antioxidant status in patients with type 1 diabetes.
Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy
Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats.
Chronic hyperglycemia and subclinical myocardial injury.
...
1
2
3
4
5
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