Alpha-lipoic acid improves acute deltamethrin-induced toxicity in rats.

  title={Alpha-lipoic acid improves acute deltamethrin-induced toxicity in rats.},
  author={Rania H. Abdou and Mohamed M Abdel-Daim},
  journal={Canadian journal of physiology and pharmacology},
  volume={92 9},
Alpha-lipoic acid (ALA) is a natural dithiol compound, with a free radical scavenger and biological antioxidant properties. The purpose of the current study was to investigate the protective effects of ALA on biochemical alteration and oxidative stress induced by acute deltamethrin intoxication in rats. Markers of liver and kidney injuries in serum of deltamethrin-intoxicated as well as ALA-pretreated rats were analyzed. Moreover, serum and (or) tissue lipid peroxidation, malondialdehyde and… CONTINUE READING
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