Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed

@article{Nordstrm2004AlphalinolenicAI,
  title={Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed},
  author={Dan C E Nordstr{\"o}m and Claes Friman and Yrj{\"o} T. Konttinen and Visa Honkanen and Yoshitsugu Nasu and Erkki Antila},
  journal={Rheumatology International},
  year={2004},
  volume={14},
  pages={231-234}
}
  • Dan C E Nordström, Claes Friman, +3 authors Erkki Antila
  • Published 2004
  • Medicine
  • Rheumatology International
  • In rheumatoid arthris s various pro-inflammatory metabolites of arachidonic acid (AA), such as leukotriene B4 (LTB4) and prostaglandin E2 (PGE2), contribute to tissue destruction and pain. [...] Key Method We, therefore, performed a placebocontrolled trial with alpha-LNA in 22 patients with rheumatoid arthritis, using a linoleic acid preparation as a placebo. After a 3-month follow-up, the treatment group showed an increased bleeding time, but the clinical, subjective (global assessment, classification of…Expand Abstract

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    Influence of dietary fatty acids on cytokine production and its clinical implications.

    VIEW 1 EXCERPT