Alpha-human atrial natriuretic polypeptide reduces the plasma arginine vasopressin concentration in human subjects.

@article{Fujio1986AlphahumanAN,
  title={Alpha-human atrial natriuretic polypeptide reduces the plasma arginine vasopressin concentration in human subjects.},
  author={Nagahisa Fujio and Masuo Ohashi and Hajime Nawata and Kiminori Kato and Hiroshi Ibayashi and Kenji Kangawa and Hisayuki Matsuo},
  journal={Clinical endocrinology},
  year={1986},
  volume={25 2},
  pages={181-7}
}
The synthetic alpha-human atrial natriuretic polypeptide (alpha-hANP) was infused into six normotensive, euvolaemic, healthy volunteers to examine the effect on the plasma arginine vasopressin (AVP) concentration. The intravenous administration of alpha-hANP (0.1 microgram/kg/min, 20 min) led to a remarkable reduction in mean blood pressure (-10 mmHg, P… CONTINUE READING