Alpha glucocorticoid receptor expression in different experimental rat models of acute lung injury.

@article{Bertorelli2008AlphaGR,
  title={Alpha glucocorticoid receptor expression in different experimental rat models of acute lung injury.},
  author={Giuseppina Bertorelli and Alberto Pesci and Silvia Peveri and Mario Mergoni and A. Bonamaotini Corradi and Anna Maria Cantoni and Giovanni Tincani and Antonio Bobbio and Michele Rusca and Paolo Carbognani},
  journal={Pulmonary pharmacology & therapeutics},
  year={2008},
  volume={21 1},
  pages={
          214-21
        }
}
BACKGROUND AND OBJECTIVES Acute respiratory distress syndrome (ARDS) is a frequent form of hypoxiemic respiratory failure caused by the acute development of diffuse lung inflammation. Dysregulated systemic inflammation with persistent elevation of circulating inflammatory cytokines is the pathogenetic mechanism for pulmonary and extrapulmonary organ dysfunction in patients with ARDS. Glucocorticoids (GCs) have a broad range of inhibitory inflammatory effects, including inhibition of cytokines… CONTINUE READING
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