[Alpha-fetoprotein suppresses keratinocyte proliferation in vitro].


The influence of alpha-fetoprotein (AFP) on the proliferation of human epidermal keratinocytes in vitro has been studied. AFP (1p microgram/ ml) inhibits the proliferation of keratinocytes cultivated in a serum-free medium. The addition of fetal bovine serum significantly enhances the effect of AFP in this culture. A similar effect of AFP is observed in a medium with a low content of calcium ions.

Cite this paper

@article{Voroteliak1996AlphafetoproteinSK, title={[Alpha-fetoprotein suppresses keratinocyte proliferation in vitro].}, author={E. A. Voroteliak and Alexey V Vasil'ev and Sergey A Gusev and T. M. Povalii and Vasiliy V. Terskikh}, journal={Izvestiia Akademii nauk. Seriia biologicheskaia}, year={1996}, volume={1}, pages={117-20} }