Alpha-fetoprotein and albumin uptake by mouse tissues during development.

@article{Laborda1989AlphafetoproteinAA,
  title={Alpha-fetoprotein and albumin uptake by mouse tissues during development.},
  author={Jo rge Laborda and Javier Naval and Miguel Calvo and Ferm{\'i}n Lampreave and J. A. Uriel},
  journal={Biology of the neonate},
  year={1989},
  volume={56 6},
  pages={332-41}
}
We have studied the evolution of the incorporation of alpha-fetoprotein (AFP) and albumin by mouse tissues from fetal to adult life. Mice were injected with 125I-labelled AFP or albumin and, 3 h later, blood and organs were removed and analyzed for their radioactive protein content. Results showed that all immature tissues examined took up both AFP and albumin from blood. AFP uptake was higher during fetal and early postnatal life and decreased with age. In general, the relative uptake of… CONTINUE READING
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