Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond.

  title={Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond.},
  author={Kuang-Kai Liu and Mei-fang Chen and Po-Yi Chen and T. Lee and C. Cheng and C. Chang and Y. Ho and Jui-I Chao},
  volume={19 20},
  • Kuang-Kai Liu, Mei-fang Chen, +5 authors Jui-I Chao
  • Published 2008
  • Chemistry, Medicine
  • Nanotechnology
  • Biological molecules conjugating with nanoparticles are valuable for applications including bio-imaging, bio-detection, and bio-sensing. Nanometer-sized diamond particles have excellent electronic and chemical properties for bio-conjugation. In this study, we manipulated the carboxyl group produced on the surface of nanodiamond (carboxylated nanodiamond, cND) for conjugating with alpha-bungarotoxin (α-BTX), a neurotoxin derived from Bungarus multicinctus with specific blockade of alpha7… CONTINUE READING
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