Alpha- and beta-synuclein expression in Parkinson disease with and without dementia.

Abstract

Parkinson disease (PD) is the most important movement disorder and about 50% of patients develop dementia over the time. PD belongs to the group of Lewy body disorders. Alpha-synuclein (AS) is the main component of Lewy bodies and its aggregation is a key event in the pathogenesis of PD. Beta-synuclein (BS) inhibits AS aggregation in vitro and in vivo and… (More)
DOI: 10.1016/j.jns.2011.05.049

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Cite this paper

@article{Beyer2011AlphaAB, title={Alpha- and beta-synuclein expression in Parkinson disease with and without dementia.}, author={Katrin Beyer and Lourdes Ispierto and Pilar Latorre and Eduardo Tolosa and Aurelio Ariza}, journal={Journal of the neurological sciences}, year={2011}, volume={310 1-2}, pages={112-7} }