• Medicine
  • Published in
    Canadian journal of genetics…
    1982

Alpha-amanitin resistance in three wild strains of Drosophila melanogaster.

@article{Phillips1982AlphaamanitinRI,
  title={Alpha-amanitin resistance in three wild strains of Drosophila melanogaster.},
  author={John P. Phillips and Judith Willms and Alexander Pitt},
  journal={Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie},
  year={1982},
  volume={24 2},
  pages={
          151-62
        }
}
Three wild strains of D. melanogaster have been identified which are resistant to normally lethal levels of the fungal toxin, alpha-amanitin. Dietary LD50S for Oregon-R, the reference strain, and Ama-KTT, Ama-MI and Ama-KLM, the resistant strains, are 1.2, 35, 30 and 10 micrograms alpha-amanitin/vial, respectively. Resistance in all three strains is a digenic trait, being determined by two independently acting dominant genes, Ama-1, Ama-2, either of which is sufficient to confer resistance and… CONTINUE READING

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Long-Term Resistance of Drosophila melanogaster to the Mushroom Toxin Alpha-Amanitin

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