Corpus ID: 914426

Alpha adrenoceptor subtypes involved in the emetic action in dogs.

  title={Alpha adrenoceptor subtypes involved in the emetic action in dogs.},
  author={Y. Hikasa and S. Ogasawara and K. Takase},
  journal={The Journal of pharmacology and experimental therapeutics},
  volume={261 2},
In order to assess the involvement of alpha-1 and alpha-2 adrenoceptors in emesis, the emetic effect of eight alpha agonists was studied in dogs. The i.m. administration of each agonist elicited dose-dependent emesis. The order of potency in inducing emesis was: clonidine greater than oxymetazoline greater than tramazoline greater than naphazoline greater than xylazine greater than epinephrine greater than methoxamine = phenylephrine. The clonidine-induced emesis was antagonized by adrenoceptor… Expand
Neurohormonal and metabolic effects of medetomidine compared with xylazine in beagle dogs.
  • T. Ambrisko, Y. Hikasa
  • Biology, Medicine
  • Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
  • 2002
The veterinary experience