Alpha-adrenergic blockade improves recovery of myocardial perfusion and function after coronary stenting in patients with acute myocardial infarction.

@article{Gregorini1999AlphaadrenergicBI,
  title={Alpha-adrenergic blockade improves recovery of myocardial perfusion and function after coronary stenting in patients with acute myocardial infarction.},
  author={Luisa Gregorini and Jean Marco and Michaela Koz{\`a}kov{\`a} and Carlo Palombo and Gian Battista Anguissola and Isabelle Marco and Monique Bernies and Bernard Cassagneau and Alessandro Distante and Irene Maria Bossi and Jean Fajadet and Gerd Heusch},
  journal={Circulation},
  year={1999},
  volume={99 4},
  pages={482-90}
}
BACKGROUND AMI reperfusion by thrombolysis does not improve TIMI flow and LV function. The role of infarct-related artery (IRA) stenosis and superimposed changes in coronary vasomotor tone in maintaining LV dysfunction must be elucidated. METHODS AND RESULTS Forty patients underwent diagnostic angiography 24 hours after thrombolysis. Seventy-two hours after thrombolysis, the culprit lesion was dilated with coronary stenting. During angioplasty, LV function was monitored by transesophageal… CONTINUE READING

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