Alpha-L-fucose: a potentially critical molecule in pathologic processes including neoplasia.

  title={Alpha-L-fucose: a potentially critical molecule in pathologic processes including neoplasia.},
  author={Jay J. Listinsky and Gene P. Siegal and Catherine M. Listinsky},
  journal={American journal of clinical pathology},
  volume={110 4},
Alpha-L-fucose is a 6-carbon deoxyhexose that is commonly incorporated into human glycoproteins and glycolipids. It is found at the terminal or preterminal positions of many cell-surface oligosaccharide ligands that mediate cell-recognition and adhesion-signaling pathways. These include such normal events as early embryologic development and blood group recognition and pathologic processes including inflammation, infectious disease recognition, and neoplastic progression. Fucosylated… CONTINUE READING


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