Alpha-Delta Sleep in Patients With a Chief Complaint of Chronic Fatigue

  title={Alpha-Delta Sleep in Patients With a Chief Complaint of Chronic Fatigue},
  author={Peter Manu and Thomas J. Lane and Dale A. Matthews and Richard J. Castriotta and R K Watson and Micha Abeles},
  journal={Southern Medical Journal},
Our prospective, standardized cohort study was designed to assess the presence of alpha wave intrusions during non-rapid eye movement sleep (alpha-delta sleep) and its relationship to fibromyalgia, major depression, and chronic fatigue syndrome (CFS) in patients with a chief complaint of chronic fatigue. The study group comprised 30 consecutive patients seen at a university hospital referral clinic for evaluation of chronic fatigue. All patients had nocturnal polysomnography, dolorimetric… 

How significant are primary sleep disorders and sleepiness in the chronic fatigue syndrome?

It is unlikely that CFS is simply a somatic expression of any PSD observed in the sample or of sleepiness per se, as the presence of PSD or sleepiness was not associated with any of the clinical scales that were used to measure anxiety, depression, somatisation, physical or mental fatigue, or functional status impairment.

Are there sleep-specific phenotypes in patients with chronic fatigue syndrome? A cross-sectional polysomnography analysis

The results highlight the need to routinely screen for Primary Sleep Disorders in clinical practice and tailor sleep interventions, based on phenotype, to patients presenting with CFS.

Sleep assessment in a population-based study of chronic fatigue syndrome

SAQ© factors describe sleep abnormalities associated with CFS and provide more information than the Epworth score, consistent with studies finding that, while fatigued, CFS subjects are not sleepy.

Respiratory sleep disorders and fibromyalgia.

  • S. Roizenblatt
  • Medicine, Psychology
    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
  • 2006
Fibromyalgia is a chronic, painful condition that is diagnosed by identifying chronic, diffuse muscular-skeletal pain upon compression of at least eighteen determined anatomical points and nonrestorative sleep is an important aspect that necessitates the investigation of primary sleep disorders in the evaluation of affected patients.

Alpha sleep characteristics in fibromyalgia.

Phasic alpha sleep activity was the pattern that correlated better with clinical manifestations of fibromyalgia and exhibited less total sleep time than patients in other subgroups, as well as lower sleep efficiency and less slow wave sleep than patients with a tonic alphaSleep pattern.

Fatigue and sleep disorders.

Prevalence and correlates of alpha-delta sleep in major depressive disorders.

Alpha-delta sleep is associated with daytime sleepiness in patients with major depressive disorder and the prevalence and clinical correlates of alpha-d delta sleep in major depressive Disorder were identified.

Subjective fatigue and subjective sleepiness: two independent consequences of sleep disorders?

The notion that subjective fatigue and sleepiness can be independent manifestations of sleep disorders is supported, and predominantly fatigued individuals with sleep disorders seem vulnerable to additional negative consequences due to possible interplay between amplified fatigue and psychological distress.

Pain and the alpha-sleep anomaly: a mechanism of sleep disruption in facioscapulohumeral muscular dystrophy.

Sleep macrostructure parameters and alpha/delta EEG power ratio during non rapid eye movement (NREM) sleep were compared between patients with and without pain, and an increased occurrence of the alpha and beta rhythms during NREM sleep in FSHD patients with pain was documented.