Alpha Amylase Is a Major Allergenic Component in Occupational Asthma Patients Caused by Porcine Pancreatic Extract*

  title={Alpha Amylase Is a Major Allergenic Component in Occupational Asthma Patients Caused by Porcine Pancreatic Extract*},
  author={Hae-Sim Park and Hee-Yeon Kim and Y. Suh and Soo-Jin Lee and Soo-Keol Lee and Sun-Sin Kim and D. Nahm},
  journal={Journal of Asthma},
  pages={511 - 516}
Porcine pancreatic extracts (PPE) are composed of α-amylase and lipase, which are common components of digestive enzymes. They have been known to cause occupational asthma in exposed workers in pharmaceutical and baking industries, as well as in a laboratory technician, but there has been no report of PPE-induced occupational asthma in medical personnel and their IgE binding components to each component. Four asthmatic subjects showing positive results on PPE-bronchoprovocation testing were… Expand
A Case of Occupational Rhinitis Caused by Porcine Pancreatic Extract Developing into Occupational Asthma
Occupational allergy to fungal lipase in the pharmaceutical industry.
Sensitization to Empynase®(pronase B) in exposed hospital personnel and identification of the Empynase® allergen
Recent developments in airway and nose occupational sensitizers
Nasal Provocation Test in the Diagnosis of Allergic Rhinitis
Facial rash and palmoplantar pruritus in an infant after first contact with kaki.


New occupational allergen in a pharmaceutical industry: serratial peptidase and lysozyme chloride.
  • H. Park, D. Nahm
  • Medicine
  • Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • 1997
Occupational asthma caused by alpha-amylase inhalation: clinical and immunologic findings and bronchial response patterns.
Occupational lung disease following long-term inhalation of pancreatic extracts.
Baker's asthma
Occupational asthma induced by inhaled egg lysozyme.
Occupational asthma due to porcine pancreatic amylase.
Occupational asthma due to pepsin.