Alpha 2A-adrenergic receptors are present in lower brainstem catecholaminergic and serotonergic neurons innervating spinal cord.

@article{Guyenet1994Alpha2R,
  title={Alpha 2A-adrenergic receptors are present in lower brainstem catecholaminergic and serotonergic neurons innervating spinal cord.},
  author={Patrice G Guyenet and Ruth L Stornetta and Timothy M. Riley and F R Norton and Diane. L. Rosin and Kevin R Lynch},
  journal={Brain research},
  year={1994},
  volume={638 1-2},
  pages={285-94}
}
A subtype-specific polyclonal antibody was used for the immunohistochemical detection of alpha 2A-adrenergic receptors (alpha 2A-ARs) in the rat lower brainstem (medulla and pons). Using dual-label fluorescence histochemistry, punctate alpha 2A-AR-like immunoreactivity (alpha 2A-AR-LIR) was identified in noradrenergic, adrenergic, and serotonergic neurons of the pontomedullary region. Confocal microscopic examination of material simultaneously labeled for TH-LIR and alpha 2A-LIR revealed that… CONTINUE READING
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