Alpha-2A adrenergic receptor gene variants are associated with increased intra-individual variability in response time

@article{Cummins2014Alpha2AAR,
  title={Alpha-2A adrenergic receptor gene variants are associated with increased intra-individual variability in response time},
  author={Tarrant D. R. Cummins and Oscar Jacoby and Ziarih Hawi and L. Sanjay Nandam and Molly Byrne and B Kim and Joseph L. Wagner and Christopher D. Chambers and Mark A. Bellgrove},
  journal={Molecular Psychiatry},
  year={2014},
  volume={19},
  pages={1031-1036}
}
Intra-individual variability in response time has been proposed as an important endophenotype for attention deficit hyperactivity disorder (ADHD). Here we asked whether intra-individual variability is predicted by common variation in catecholamine genes and whether it mediates the relationship between these gene variants and self-reported ADHD symptoms. A total of 402 non-clinical Australian adults of European descent completed a battery of five cognitive tasks and the Conners’ Adult ADHD… CONTINUE READING
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