Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms.

@article{Weeratunga2012Alpha1GI,
  title={Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms.},
  author={Saroja K Weeratunga and Asiah Osman and Nien-Jen Hu and Conan K. L. Wang and Lyndel Mason and Staffan G. Sv{\"a}rd and Greg A Hope and Malcolm Kenneth Jones and Andreas Hofmann},
  journal={Journal of molecular biology},
  year={2012},
  volume={423 2},
  pages={169-81}
}
Alpha-giardins constitute the annexin proteome (group E annexins) in the intestinal protozoan parasite Giardia and, as such, represent the evolutionary oldest eukaryotic annexins. The dominance of alpha-giardins in the cytoskeleton of Giardia with its greatly reduced actin content emphasises the importance of the alpha-giardins for the structural integrity… CONTINUE READING