Alpha 1 antitrypsin polymorphism in the Tunisian population with special reference to pulmonary disease.

@article{Denden2008Alpha1A,
  title={Alpha 1 antitrypsin polymorphism in the Tunisian population with special reference to pulmonary disease.},
  author={Sabri Denden and Amel Haj Khelil and P. Perrin and Houria Daimi and Nadia Leban and A Ouaja and Kacem Mahdouani and L. Hlioui and G{\'e}rard Lefranc and Jemni Ben Chibani},
  journal={Pathologie-biologie},
  year={2008},
  volume={56 3},
  pages={
          106-10
        }
}
OBJECTIVES The study investigated alpha 1 antitrypsin (AAT) gene polymorphism in the Tunisian population. We aimed to analyze the correlation between Pi polymorphism and the risk of developing chronic obstructive pulmonary disease (COPD). PATIENTS AND METHODS We focused our study on two samples originating from the Tunisian centre: 318 healthy controls and 90 patients suffering from COPD. Data analysis was investigated by AAT level quantification, serum isoelectric focusing (IEF) and RFLP-PCR… CONTINUE READING
BETA