Alpha 1-adrenoceptors: subtypes, signaling, and roles in health and disease.

@article{GarcaSinz1999Alpha1S,
  title={Alpha 1-adrenoceptors: subtypes, signaling, and roles in health and disease.},
  author={Jes{\'u}s Adolfo Garc{\'i}a-S{\'a}inz and Jos{\'e} V{\'a}zquez-Prado and Rafael Villalobos-Molina},
  journal={Archives of medical research},
  year={1999},
  volume={30 6},
  pages={449-58}
}
Alpha 1-adrenoceptors mediate some of the main actions of the natural catecholamines, adrenaline, and noradrenaline. They participate in many essential physiological processes, such as sympathetic neurotransmission, modulation of hepatic metabolism, control of vascular tone, cardiac contraction, and the regulation of smooth muscle activity in the genitourinary system. It is now clear that alpha 1-adrenoceptors mediate, in addition to immediate effects, longer term actions of catecholamines such… CONTINUE READING