Alloxan in the treatment of a case of islet cell carcinoma of the pancreas with liver metastases.

@article{Flinn1947AlloxanIT,
  title={Alloxan in the treatment of a case of islet cell carcinoma of the pancreas with liver metastases.},
  author={L. B. Flinn and E. Minnick and D. M. Gay},
  journal={Annals of internal medicine},
  year={1947},
  volume={26 6},
  pages={
          936-45
        }
}
Excerpt Organic hyperinsulinism has been recognized with increasing frequency in the last few years. It is most commonly due to adenomata of the islands of Langerhans. More and more case reports ap... 
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  • 1953
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References

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CARCINOMA OF THE ISLANDS OF LANGERHANS WITH HYPOGLYCEMIA AND METASTASIS TO THE LIVER
TLDR
Hypoglycemia may be due to many causes—pituitary tumors; adrenal cortical tumors; advanced hepatic disease such as yellow atrophy, carcinoma or fatty infiltration; cachectic states; excessive physical exercise, and, most spectacularly, to tumors of the island cells of the pancreas. Expand
THE MECHANISM OF ACTION OF ALLOXAN ON BLOOD SUGAR
TLDR
In pancreatectomized toads, alloxan injected immediately after the operation either prevents or decreases the diabetic hyperglycemia during the next 24 hours, as shown by the blood samples 24 hours after injection. Expand