• Corpus ID: 40905352

Alloxan in refined flour : A Diabetic concern

@inproceedings{Banu2012AlloxanIR,
  title={Alloxan in refined flour : A Diabetic concern},
  author={Shakila Banu},
  year={2012}
}
Diabetes mellitus has been considered as one of the major health concerns all around the world today. The newest tainted food supply concern is that flour in commonly consumed baked goods is being bleached with chloride oxide that produces alloxan as a byproduct, leading to toxic effect on Beta cells of the pancreas. This causes an insulin-dependent diabetes mellitus also called as "Alloxan Diabetes". Alloxan is a well-known and universally used agent for evoking experimental insulin dependent… 

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References

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Alloxan Induced Diabetes: Mechanisms and Effects
TLDR
The mechanism of action of alloxan in order to induce diabetes mellitus in experimental animals is highlighted and it is found to be selectively toxic to pancreatic beta cells.
Induction of type-1 diabetes mellitus in laboratory rats by use of alloxan: route of administration, pitfalls, and insulin treatment.
TLDR
In attempting to induce type-1 DM in Sprague-Dawley rats, it was found that multiple doses of alloxan led to significantly higher mortality than did a single dose and a single high dose was the best treatment.
Ac., OMD Chemical Causes of Diabetes: Overeating
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