Alloxan action on glucose metabolism in cultured fibroblasts. I. Stimulation and inhibition of glucose utilization.

@article{Ishibashi1981AlloxanAO,
  title={Alloxan action on glucose metabolism in cultured fibroblasts. I. Stimulation and inhibition of glucose utilization.},
  author={Fukashi Ishibashi and Hiroyoshi Hidaka and Regina M Fields and Barbara V Howard and Peter H. Bennett},
  journal={The American journal of physiology},
  year={1981},
  volume={240 6},
  pages={E640-4}
}
The influence of alloxan on mammalian cell glucose metabolism has been investigated using human diploid fibroblastic cells in culture. When cell monolayers were exposed to D-[14C]glucose, the presence of alloxan (0.31-1.87 mM) resulted initially in a dose-dependent enhancement of total cell glucose incorporation. This was observed within 2 min and declined… CONTINUE READING