Allosensitization and outcomes in pediatric heart transplantation.

  title={Allosensitization and outcomes in pediatric heart transplantation.},
  author={William T. Mahle and Margaret A. Tresler and R. Erik Edens and Paolo Rusconi and James F. George and David C. Naftel and Robert E. Shaddy},
  journal={The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation},
  volume={30 11},
BACKGROUND Allosensitization among children being considered for heart transplantation remains a great challenge. Controversy exists as to the best approach for those with elevated panel-reactive antibody (PRA) titers. We sought to define the association between elevated PRA and outcomes using data from the multi-institutional Pediatric Heart Transplant Study Group. METHODS Between January 1993 and December 2008, 3,016 patients (>1 month of age) were listed for heart transplantation. PRA data… CONTINUE READING


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