Allorecognition Proteins in an Invertebrate Exhibit Homophilic Interactions

  title={Allorecognition Proteins in an Invertebrate Exhibit Homophilic Interactions},
  author={Uma B. Karadge and Minja Gosto and Matthew L. Nicotra},
  journal={Current Biology},
Sessile colonial invertebrates-animals such as sponges, corals, bryozoans, and ascidians-can distinguish between their own tissues and those of conspecifics upon contact [1]. This ability, called allorecognition, mediates spatial competition and can prevent stem cell parasitism by ensuring that colonies only fuse with self or close kin. In every taxon studied to date, allorecognition is controlled by one or more highly polymorphic genes [2-8]. However, in no case is it understood how the… CONTINUE READING

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