Allopurinol as a cardioprotectant during coronary artery bypass graft surgery.

@article{Weimert2003AllopurinolAA,
  title={Allopurinol as a cardioprotectant during coronary artery bypass graft surgery.},
  author={Nicole A Weimert and William F Tanke and Jeffery J Sims},
  journal={The Annals of pharmacotherapy},
  year={2003},
  volume={37 11},
  pages={1708-11}
}
OBJECTIVE To examine the role of allopurinol as a cardioprotectant during coronary artery bypass graft (CABG) surgery. DATA SOURCES A search of MEDLINE (1966-October 2002) was performed using the following terms: allopurinol, xanthine oxidase, oxygen free radical, and coronary artery bypass. References evaluated were limited to English-language and human studies, yielding 41 citations, 13 of which were found suitable. The 5 largest studies are discussed. DATA SYNTHESIS Multiple studies with… CONTINUE READING