Allografts of CNS tissue possess a blood-brain barrier. I. Grafts of medial preoptic area in hypogonadal mice.

@article{Broadwell1989AllograftsOC,
  title={Allografts of CNS tissue possess a blood-brain barrier. I. Grafts of medial preoptic area in hypogonadal mice.},
  author={R. D. Broadwell and Harry M. Charlton and William F. Ganong and Michael Salcman and Michael V Sofroniew},
  journal={Experimental neurology},
  year={1989},
  volume={105 2},
  pages={135-51}
}
This study represents the first part of a three-part investigation of blood vessels supplying CNS tissue transplanted within the brains of adult mammalian hosts. The results emphasize that blood vessels in solid CNS grafts contribute a blood-brain barrier to that of the host. Neurosecretory cells in basal forebrain grafts placed intraventricularly on the dorsal surface of the host median eminence, a neurosecretory site containing fenestrated blood vessels, do not stimulate similar blood vessels… CONTINUE READING

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