Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia.

  title={Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia.},
  author={Jerald P Radich and Eduardo Olavarr{\'i}a and Jane F. Apperley},
  journal={Hematology/oncology clinics of North America},
  volume={18 3},
  pages={685-702, x}
There never has been a more difficult time to advise patients newly diagnosed with chronic myeloid leukemia (CML). Until recently,the options comprised noncurative but relatively nontoxic chemotherapy or potentially curative allogeneic stem cell transplantation,with its attendant morbidity and mortality. There now is the additional option of the tyrosine kinase inhibitor imatinib mesylate that has been in clinical practice for almost 5 years. Although data are emerging regarding the efficacy of… CONTINUE READING
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