Allogeneic bone marrow transplantation with reduced intensity conditioning for chronic granulomatous disease complicated by invasive Aspergillus infection.

@article{Sastry2006AllogeneicBM,
  title={Allogeneic bone marrow transplantation with reduced intensity conditioning for chronic granulomatous disease complicated by invasive Aspergillus infection.},
  author={Jairam Sastry and Alyson M Kakakios and Heidi Tugwell and Peter A. Shaw},
  journal={Pediatric blood & cancer},
  year={2006},
  volume={47 3},
  pages={
          327-9
        }
}
Chronic granulomatous disease (CGD) is a rare disorder characterized by recurrent infections, often resulting in impaired quality of life and death. Allogeneic BMT provides a definitive cure for CGD, but carries a significant risk of mortality and morbidity. The risk is higher for those who have invasive fungal infection prior to transplant. Reduced intensity conditioning (RIC) is associated with less toxicity from the conditioning agents and may provide an alternative option for all non… CONTINUE READING
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