Allogeneic bone marrow transplantation for patients with high-risk acute lymphoblastic leukemia.

@article{Wingard1990AllogeneicBM,
  title={Allogeneic bone marrow transplantation for patients with high-risk acute lymphoblastic leukemia.},
  author={John R Wingard and Steve Piantadosi and George W. Santos and Rein Saral and Huibert M Vriesendorp and Andrew M. Yeager and W H Burns and Richard Frederick Ambinder and Hayden G. Braine and G E Elfenbein},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1990},
  volume={8 5},
  pages={820-30}
}
Seventy-four consecutive patients with high-risk acute lymphoblastic leukemia (ALL) were given cyclophosphamide (CY; 50 mg/kg on each of 4 days) plus total body irradiation (TBI; 300 rad on each of 4 days) followed by a human leukocyte antigen (HLA)-identical allogeneic bone marrow transplant (BMT). Eighteen patients in first complete remission (CR1), 36 in CR2, 16 in CR3, and four in CR4 were transplanted. Patients in CR1 were transplanted 1 to 8 months (median, 3 months) after attaining CR… CONTINUE READING
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