Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival.

@article{Neudorf2004AllogeneicBM,
  title={Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival.},
  author={Steven M L Neudorf and Jean E. Sanders and Nathan L. Kobrinsky and Todd A Alonzo and Allen B. Buxton and Stuart Gold and Dorothy R Barnard and Joetta DeSwarte Wallace and Dagmar K. Kalousek and Beverly J. Lange and William G A Woods},
  journal={Blood},
  year={2004},
  volume={103 10},
  pages={3655-61}
}
In Children's Cancer Group (CCG) study 2891, patients who were recently diagnosed with acute myelocytic leukemia (AML) were assigned randomly to standard- or intensive-timing induction chemotherapy. Patients in first complete remission (CR1) and who had a human leukocyte antigen (HLA)-identical, related donor or a donor disparate at a single class I or II locus were nonrandomly assigned to receive a bone marrow transplant (BMT) by using oral busulfan (16 mg/kg) and cyclophosphamide (200 mg/kg… CONTINUE READING
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