Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms

@article{Jensen2014AllodyniaAH,
  title={Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms},
  author={Troels Staehelin Jensen and Nanna Brix Finnerup},
  journal={The Lancet Neurology},
  year={2014},
  volume={13},
  pages={924-935}
}
Allodynia (pain due to a stimulus that does not usually provoke pain) and hyperalgesia (increased pain from a stimulus that usually provokes pain) are prominent symptoms in patients with neuropathic pain. Both are seen in various peripheral neuropathies and central pain disorders, and affect 15-50% of patients with neuropathic pain. Allodynia and hyperalgesia are classified according to the sensory modality (touch, pressure, pinprick, cold, and heat) that is used to elicit the sensation… Expand

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