Allocation concealment in randomised trials: defending against deciphering

@article{Schulz2002AllocationCI,
  title={Allocation concealment in randomised trials: defending against deciphering},
  author={K. Schulz and D. Grimes},
  journal={The Lancet},
  year={2002},
  volume={359},
  pages={614-618}
}
Proper randomisation rests on adequate allocation concealment. An allocation concealment process keeps clinicians and participants unaware of upcoming assignments. Without it, even properly developed random allocation sequences can be subverted. Within this concealment process, the crucial unbiased nature of randomised controlled trials collides with their most vexing implementation problems. Proper allocation concealment frequently frustrates clinical inclinations, which annoys those who do… Expand

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