Alloantibody from a patient with severe von Willebrand disease inhibits von Willebrand factor-FVIII interaction

@article{Batlle1997AlloantibodyFA,
  title={Alloantibody from a patient with severe von Willebrand disease inhibits von Willebrand factor-FVIII interaction},
  author={Javier Batlle and Esther Lour{\'e}s and P. C. Fern{\'a}ndez Vila and Mar{\'i}a del Carmen Rodr{\'i}guez - Hern{\'a}ndez and Jairo Andr{\'e}s M{\'e}ndez and Jorge Horacio Torea and Esther Rendal and M. J. Couselo and Agostinho Filgueira and M. F. L{\'o}pez Fern{\'a}ndez},
  journal={Annals of Hematology},
  year={1997},
  volume={75},
  pages={111-115}
}
 The aim of this study was to analyze the ability of an alloantibody from a patient with severe von Willebrand disease (vWD) to interfere with the vWF domain for FVIII, to inhibit factor VIII (FVIII), and to compare it with a rabbit polyclonal antibody. The vWF domain for binding to FVIII was assayed by a method previously described but using recombinant FVIII (r-FVIII, Kogenate), which contains no vWF, instead of Hemofil M (HM). Rabbit or human antibodies towards FVIII (FVIII-Ab) were analyzed… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 29 references

Antibody nature of circulating inhibitor of plasma von Willebrand factor.

Proceedings of the National Academy of Sciences of the United States of America • 1975
View 4 Excerpts
Highly Influenced

A case of recessive type 2N von Willebrand’s disease due to Arg 53 Trp substitution

M Pérez Casal, M Daily, I Peake, J Batlle
Am J Hematol • 1995
View 1 Excerpt

An alloantibody to von Willebrand factor selectively inhibiting the binding of von Willebrand factor to collagen in a patient with severe von Willebrand disease

U Budde, W Effenberg, +4 authors HH Brackmann
Thromb Haemost • 1995
View 1 Excerpt

Apparent IgG anti-factor VIII antibodies in normal individuals are specific for ABO blood group substances

JC Gill, K Stephany, D Newton-Nash, PA Foster
1995
View 1 Excerpt

parent IgG anti - factor VIII antibodies in normal individuals are specific for ABO

JC Gill, K Stephany, D Newton-Nash, PA Foster
BLOOD • 1995

Further evidence for recessive inheritance of von Willebrand disease with abnormal binding of von Willebrand factor to factor VIII

MF López Fernández, MJ Blanco López, MP Castiñeira, J Batlle
Am J Hematol • 1992
View 3 Excerpts

Natural antibodies to factor VIII (anti-hemophilic factor) in healthy individuals.

Proceedings of the National Academy of Sciences of the United States of America • 1992
View 1 Excerpt

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