Alleviating neurodegeneration in Drosophila models of PolyQ diseases

Abstract

Polyglutamine (polyQ) diseases are a group of neurodegenerative conditions, induced from CAG trinucleotide repeat expansion within causative gene respectively. Generation of toxic proteins, containing polyQ-expanded tract, is the key process to cause neurodegeneration. Till now, although polyQ diseases remain uncurable, numerous therapeutic strategies with… (More)
DOI: 10.1186/2053-8871-1-9

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Cite this paper

@inproceedings{Long2014AlleviatingNI, title={Alleviating neurodegeneration in Drosophila models of PolyQ diseases}, author={Zhe Long and Bei-sha Tang and Hong Jiang}, booktitle={Cerebellum & Ataxias}, year={2014} }