Allethrin differentially modulates voltage-gated calcium channel subtypes in rat PC12 cells.

@article{Neal2010AllethrinDM,
  title={Allethrin differentially modulates voltage-gated calcium channel subtypes in rat PC12 cells.},
  author={A. P. Neal and Y. Yuan and W. Atchison},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2010},
  volume={116 2},
  pages={
          604-13
        }
}
Pyrethroid insecticides are one of the most widely used classes of insecticides. Previous studies revealed that pyrethroids potently affect the insect voltage-gated sodium (Na(+)) channel (VGSC), resulting in prolonged channel open time. However, recent findings have suggested that pyrethroids may affect targets other than the VGSC. In particular, several studies have shown that pyrethroids can modulate the activity of voltage-gated calcium (Ca(2+)) channels (VGCCs). However, these studies… Expand
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