Allergy, parasites, and the hygiene hypothesis.

  title={Allergy, parasites, and the hygiene hypothesis.},
  author={M. Yazdanbakhsh and P. Kremsner and R. van Ree},
  volume={296 5567},
  • M. Yazdanbakhsh, P. Kremsner, R. van Ree
  • Published 2002
  • Biology, Medicine
  • Science
  • The increase of allergic diseases in the industrialized world has often been explained by a decline in infections during childhood. The immunological explanation has been put into the context of the functional T cell subsets known as T helper 1 (TH1) and T helper 2 (TH2) that display polarized cytokine profiles. It has been argued that bacterial and viral infections during early life direct the maturing immune system toward TH1, which counterbalance proallergic responses of TH2 cells. Thus, a… CONTINUE READING
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