Allergome: the characterization of allergens based on a 2D gel electrophoresis approach.

@article{Chardin2005AllergomeTC,
  title={Allergome: the characterization of allergens based on a 2D gel electrophoresis approach.},
  author={H{\'e}l{\`e}ne Chardin and Gabriel Peltre},
  journal={Expert review of proteomics},
  year={2005},
  volume={2 5},
  pages={757-65}
}
Type I hypersensitivity reactions are in constant progression in industrialized countries. The physiopathologic mechanism of these diseases implicates the production of specific immunoglobulin (Ig)E to allergenic molecules, their binding to the Fcepsilon receptor on the surface of mast cells and basophils, and the release of inflammatory mediators when allergens are introduced into the body and crosslink with the IgE bound to the cell surface. An allergen is defined as a molecule that induces… CONTINUE READING