Allergic transfusion reactions to platelets are associated more with recipient and donor factors than with product attributes.

@article{Savage2011AllergicTR,
  title={Allergic transfusion reactions to platelets are associated more with recipient and donor factors than with product attributes.},
  author={William J. Savage and Aaron A. R. Tobian and Alice K Fuller and Robert B. Wood and Karen E. King and Paul M. Ness},
  journal={Transfusion},
  year={2011},
  volume={51 8},
  pages={1716-22}
}
BACKGROUND Mechanisms of allergic transfusion reactions (ATRs) are not well understood. The aim of this study was to distinguish recipient-, donor-, and product-specific factors associated with ATRs. STUDY DESIGN AND METHODS We conducted a retrospective cohort study of apheresis platelet (AP) products transfused from April 2000 through March 2010. The concordance rate of ATRs when split AP products were transfused to at least two individuals was compared to the overall ATR rate among all AP… CONTINUE READING