Allergic reactions to the first COVID‐19 vaccine: A potential role of polyethylene glycol?
@article{Cabanillas2020AllergicRT, title={Allergic reactions to the first COVID‐19 vaccine: A potential role of polyethylene glycol?}, author={Beatriz Cabanillas and Cezmi A. Akdis and Natalija Novak}, journal={Allergy}, year={2020}, volume={76} }
The COVID-19 vaccine developed by Pfizer and BioNTech was approved by the Medicines and Healthcare Products Regulatory Agency (MHRA) in the United Kingdom (UK) on December 2nd 2020.1 MHRA is therefore the first regulator agency in the world to approve a vaccine to prevent coronavirus disease (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a virus that is responsible for a global pandemic.
76 Citations
Cutaneous and Allergic reactions due to COVID‐19 vaccinations: A review
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The pandemic caused by the novel coronavirus disease 2019 (COVID‐19) has had an unprecedented impact on the overall health and the global economy. Vaccination is currently the most dependable…
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COVID‐19 vaccines and the role of other potential allergenic components different from PEG. A reply to: “Other excipients than PEG might cause serious hypersensitivity reactions in COVID‐19 vaccines”
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To the Editor, Thank you for the correspondence of Borgsteede et al “Other excipients than PEG might cause serious hypersensitivity reactions in COVID19 vaccines.”1 We agree with the authors and…
A Bullous Eruption following the Pfizer‐BioNTech COVID‐19 vaccination
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An ongoing multinational randomised controlled trial assessing the safety of the Pfizer-BioNTech COVID-19 vaccine reported few localized cutaneous reactions at the injection site, but no significant adverse cutaneous allergic reactions.
Practical handling of allergic reactions to COVID-19 vaccines
- MedicineAllergo Journal International
- 2021
Recommendations for prophylaxis, diagnosis and therapy of these allergic reactions are given by a panel of experts, and allergy workup is recommended, as it is for a small potential risk population prior to the first vaccination.
Who Is Really at Risk for Anaphylaxis Due to COVID-19 Vaccine?
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COVID-19 Vaccine Anaphylaxis: Current Evidence and Future Approaches
- Medicine, BiologyFrontiers in Allergy
- 2021
Skin testing, using the basophil activation test, has been used to clarify the mechanism of the anaphylaxis and provide safety information for the next injection and suggested approaches for patients who experienced an immediate severe allergic reaction to the first dose of a COVID-19 vaccine.
Adverse rare events to vaccines for COVID-19: From hypersensitivity reactions to thrombosis and thrombocytopenia
- BiologyInternational reviews of immunology
- 2021
An updated review of the last scientific findings that can explain the rare side effects that the vaccines for COVID-19 can produce is provided.
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Polyethylene glycol as a cause of anaphylaxis
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A case of anaphylaxis caused by macrogol 3350 after injection of a corticosteroid
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Macrogols are polymers of ethylene glycol, and are widely used in food and food packaging, and also in cosmetics and pharmaceutical preparations as solvents, softening agents, and lubricants.
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