Allergic reactions to oxaliplatin in a single institute in Japan.

  title={Allergic reactions to oxaliplatin in a single institute in Japan.},
  author={Yasushi Ichikawa and Ayumu Goto and Satoru Hirokawa and Miyuki Kijima and Takashi Ishikawa and Takashi Chishima and Hirokazu Suwa and Harumi Yamamoto and Shigeru Yamagishi and Shunichi Osada and Mitsuyoshi Ota and Shoichi Fujii},
  journal={Japanese journal of clinical oncology},
  volume={39 9},
Allergic reactions to oxaliplatin can be severe and are an important cause of discontinuation of treatment. A retrospective review was performed for 105 patients who received FOLFOX regimens between May 2005 and June 2007. Twenty-five cases (23.8%) of allergic reactions were identified, including 9 late onset reactions (8.6%) and 16 immediate reactions (15.2%). Severe allergy (Grades 3 and 4) occurred in seven patients (6.7%). Re-introduction of FOLFOX was attempted for seven immediate onset… CONTINUE READING

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