Allergic lung inflammation alters neither susceptibility to Streptococcus pneumoniae infection nor inducibility of innate resistance in mice

@article{Clement2009AllergicLI,
  title={Allergic lung inflammation alters neither susceptibility to Streptococcus pneumoniae infection nor inducibility of innate resistance in mice},
  author={Cecilia Clement and Michael J. Tuvim and Christopher M Evans and Daniel M Tuvin and Burton F Dickey and Scott E Evans},
  journal={Respiratory Research},
  year={2009},
  volume={10},
  pages={70 - 70}
}
BACKGROUND Protective host responses to respiratory pathogens are typically characterized by inflammation. However, lung inflammation is not always protective and it may even become deleterious to the host. We have recently reported substantial protection against Streptococcus pneumoniae (pneumococcal) pneumonia by induction of a robust inflammatory innate immune response to an inhaled bacterial lysate. Conversely, the allergic inflammation associated with asthma has been proposed to promote… CONTINUE READING

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Stimulation of lung innate immunity protects mice broadly against bacterial and fungal pneumonia

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