Allergic fungal rhinosinusitis: current theories and management strategies.

@article{Marple2001AllergicFR,
  title={Allergic fungal rhinosinusitis: current theories and management strategies.},
  author={Bradley F. Marple},
  journal={The Laryngoscope},
  year={2001},
  volume={111 6},
  pages={1006-19}
}
The combination of nasal polyposis, crust formation, and sinus cultures yielding Aspergillus was first noted in 1976 by Safirstein,1 who observed the clinical similarity that this constellation of findings shared with allergic bronchopulmonary Aspergillosis (ABPA). Eventually this disease came to be known as allergic fungal rhinosinusitis (AFS). As clinical evidence of AFS accumulated, controversy regarding its etiology, pathogenesis, natural history, and appropriate treatment naturally emerged… CONTINUE READING