Allergic contact dermatitis.

  title={Allergic contact dermatitis.},
  author={Michael D. Gober and Anthony A. Gaspari},
  journal={Current directions in autoimmunity},
Allergic contact dermatitis is a classic example of a cell mediated hypersensitivity reaction in the skin. This occurs as a result of xenobiotic chemicals penetrating into the skin, chemically reacting with self proteins, eventually resulting in a hapten-specific immune response. It is precisely because of this localized immune response that allergic signs and symptoms occur (redness, edema, warmth and pruritus). It has been known for years that conventional T-cells (CD4+ or CD8+ T-cells that… CONTINUE READING