Allergic contact dermatitis due to 1,2-benzisothiazolin-3-one in gum arabic.

@article{Freeman1984AllergicCD,
  title={Allergic contact dermatitis due to 1,2-benzisothiazolin-3-one in gum arabic.},
  author={Susanne Freeman},
  journal={Contact dermatitis},
  year={1984},
  volume={11 3},
  pages={146-9}
}
Benzisothiazolin-3-one is a preservative widely used in industry. The manufacturer states that it is a known skin irritant and sensitiser, but these facts are not well-known. A case is described of contact allergy in a lithoprinter caused by it when used as a preservative in gum arabic. The literature is reviewed and a suitable patch-test concentration is suggested. It should be included in the patch-test battery for lithoprinters. 

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