Allergic contact dermatitis caused by ethylhexylglycerin in both an ointment and a skin aerosol.

Abstract

Case Report A 50-year-old woman developed a pruritic rash on her hands and forearms, spreading to the trunkwhile sparing the upper arms, after applying an ointment (Totes Meer Pflegebalsam®) and a skin aerosol (Panthenol Spray®) to treat irritant hand eczema caused by intensive gardening. Patch tests with the original products and several test series of the German Contact Dermatitis Research Group (baseline series, ointment bases, preservatives, and fragrances) from Almirall Hermal (Reinbek, Germany) were applied for 48h, and read at day (D)2 and D3. Positive reactions at D3 to triclosan 2% pet. (+), citronellol 1% pet. (+), and both suspected products tested ‘as is’ (++) were observed. Whereas the producer of Totes Meer Pflegebalsam® refused to provide the single components for further work-up, TUNAP (Wolfratshausen, Germany) provided the ingredients of Panthenol Spray®. Subsequent patch tests showed a positive result (++) at D2 for ethylhexylglycerin 5% pet., which was contained in both products (Table 1). Triclosan, which is frequently used in topically applied antibacterial and antifungal preparations, has been reported to be a contact allergen, albeit a rare one (6). However, our patient did

DOI: 10.1111/cod.12471

Cite this paper

@article{Harries2016AllergicCD, title={Allergic contact dermatitis caused by ethylhexylglycerin in both an ointment and a skin aerosol.}, author={Carlotta Harries and Stefan M{\"{u}hlenbein and Johannes Geier and Wolfgang Pf{\"{u}tzner}, journal={Contact dermatitis}, year={2016}, volume={74 3}, pages={181-2} }